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Nervous system : Definition, Introduction, Anatomy, Neurons and Glial Cells

 Nervous system

Table of content

  • Introduction to the Nervous System
  • Anatomy of the Nervous System
  • Neurons and Glial Cells
  • Action Potential and Synaptic Transmission
  • Central Nervous System (CNS)
  • Peripheral Nervous System (PNS)
  • Somatic Nervous System
  • Autonomic Nervous System (ANS)
  • Sympathetic and Parasympathetic Divisions of ANS
  • Sensory Systems
  • Motor Systems
  • Higher Cognitive Functions
  • Disorders of the Nervous System
  • Current Research and Future Directions in Neuroscience
  • Conclusion

Definition

The nervous system is a complex network of cells, tissues, and organs that coordinates and regulates the body's responses to internal and external stimuli. It is responsible for processing and transmitting information through electrical and chemical signals and is involved in various functions such as sensory perception, motor control, cognition, and behavior. 

Introduction to the Nervous System

The nervous system is one of the most complex and fascinating systems of the human body. It is responsible for controlling and coordinating all of our thoughts, emotions, and actions.

At its most basic level, the nervous system is made up of billions of specialized cells called neurons, which communicate with each other through electrical and chemical signals. These neurons work together to transmit and process information from the world around us, and from within our own bodies so that we can respond to changes in our environment and maintain homeostasis.

Nervous system : Definition, Introduction, Anatomy, Neurons and Glial Cells



The nervous system can be divided into two main parts: the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS is made up of the brain and spinal cord, while the PNS includes all of the nerves that branch out from the CNS to the rest of the body.

The CNS is responsible for processing and integrating sensory information from the PNS, and for generating appropriate responses in the form of motor commands. It also plays a key role in higher cognitive functions such as perception, memory, and reasoning.

The PNS is further divided into the somatic and autonomic nervous systems. The somatic nervous system controls voluntary movements and transmits sensory information from the skin, muscles, and joints. The autonomic nervous system regulates involuntary activities such as heart rate, digestion, and breathing.

The nervous system is a highly adaptable and dynamic system that is constantly changing and responding to new stimuli. It is also vulnerable to damage from injury, disease, and environmental factors. Understanding how the nervous system works and how to maintain its health is crucial for overall health and well-being.

Anatomy of the Nervous System

The nervous system is composed of two main parts: the central nervous system (CNS) and the peripheral nervous system (PNS).

The CNS consists of the brain and spinal cord. The brain is a complex and intricate organ that is responsible for many different functions such as thinking, feeling, and controlling movement. It is divided into several regions, each with its own specific functions. The spinal cord is a long, thin, tubular bundle of nervous tissue that extends from the brainstem to the lower back. It serves as a communication pathway between the brain and the rest of the body.

The PNS consists of all the nerves outside of the CNS. It is further divided into two main divisions: the somatic nervous system and the autonomic nervous system. The somatic nervous system is responsible for voluntary movements and transmits sensory information from the skin, muscles, and joints to the CNS. The autonomic nervous system controls involuntary activities such as heart rate, digestion, and breathing.

The basic unit of the nervous system is the neuron. Neurons are specialized cells that transmit information through electrical and chemical signals. They consist of a cell body, dendrites, and an axon. Dendrites receive signals from other neurons, while the axon transmits signals to other neurons or to muscles or glands.

Supporting cells called glial cells provide structural support and nutrition to neurons. There are several types of glial cells, including astrocytes, oligodendrocytes, and microglia.

Neurons and Glial Cells

Neurons and glial cells are the two main types of cells that make up the nervous system.

Neurons are specialized cells that transmit information throughout the nervous system. They consist of a cell body, dendrites, and an axon. Dendrites receive information from other neurons, while the axon transmits information to other neurons, muscles, or glands. Neurons communicate with each other through electrical and chemical signals called action potentials and neurotransmitters, respectively. There are many different types of neurons, each with its own specific function.

Glial cells, also known as neuroglia or simply glia, are non-neuronal cells that provide support and protection to neurons. They make up about half of the cells in the nervous system. There are several types of glial cells, each with its own specific function. Astrocytes provide structural support and nutrition to neurons and also help regulate the chemical environment around neurons. Oligodendrocytes and Schwann cells produce myelin, a fatty substance that insulates axons and allows for faster transmission of signals. Microglia act as the immune cells of the nervous system, protecting against infections and removing damaged cells.

Neurons and glial cells work together to maintain the structure and function of the nervous system. Dysfunction of either type of cell can lead to a variety of neurological disorders, such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis.

Action Potential and Synaptic Transmission

Action potential and synaptic transmission are the processes by which neurons communicate with each other in the nervous system.

The action potential is a brief electrical signal that is generated by the movement of ions across the cell membrane of a neuron. When a neuron receives enough stimulation, it reaches a threshold level and triggers an action potential. This electrical signal travels down the axon of the neuron and causes the release of neurotransmitters at the axon terminal.

Synaptic transmission is the process by which neurotransmitters are released from the axon terminal of one neuron and bind to receptors on the dendrites or cell body of another neuron. This binding causes changes in the electrical potential of the receiving neuron, which can lead to the generation of a new action potential.

There are two types of synapses: chemical synapses and electrical synapses. Chemical synapses are the most common type of synapse, and involve the release of neurotransmitters into the synaptic cleft, a small gap between the axon terminal and the dendrite of the receiving neuron. Electrical synapses involve the direct flow of ions between cells through gap junctions and are less common in the nervous system.

Action potential and synaptic transmission are fundamental processes that allow neurons to communicate and integrate information within the nervous system. Dysfunction of these processes can lead to a variety of neurological disorders, such as epilepsy and depression.

Central Nervous System (CNS)

The central nervous system (CNS) is composed of the brain and spinal cord and is responsible for integrating and coordinating sensory information and motor responses throughout the body.

The brain is a complex and highly specialized organ that is divided into several regions, each with its own specific functions. These regions include the cerebrum, cerebellum, and brainstem. The cerebrum is the largest and most complex region and is responsible for higher functions such as consciousness, thought, and emotion. The cerebellum is responsible for coordinating movement and balance, while the brainstem controls basic life-sustaining functions such as breathing and heart rate.

The spinal cord is a long, thin, tubular bundle of nervous tissue that extends from the brainstem to the lower back. It serves as a communication pathway between the brain and the rest of the body. The spinal cord is responsible for relaying sensory information from the body to the brain and transmitting motor commands from the brain to the muscles.

The CNS is protected by several layers of membranes called meninges, as well as cerebrospinal fluid (CSF), which provides cushioning and support. The blood-brain barrier, a specialized system of cells that lines the blood vessels in the brain, also helps protect the CNS from harmful substances.

Dysfunction of the CNS can lead to a variety of neurological disorders, such as Alzheimer's disease, Parkinson's disease, and stroke. Treatments for CNS disorders include medications, surgery, and therapies such as physical and occupational therapy.

Peripheral Nervous System (PNS)

The peripheral nervous system (PNS) is the part of the nervous system that is outside of the brain and spinal cord. It is responsible for connecting the central nervous system to the rest of the body.

The PNS is composed of two main parts: the somatic nervous system and the autonomic nervous system. The somatic nervous system is responsible for controlling voluntary movements and sensory input from the body to the brain. The autonomic nervous system is responsible for controlling involuntary functions such as heart rate, digestion, and breathing.

The autonomic nervous system is further divided into the sympathetic and parasympathetic nervous systems. The sympathetic nervous system is responsible for the "fight or flight" response, which prepares the body for intense physical activity or stressful situations. The parasympathetic nervous system, on the other hand, is responsible for the "rest and digest" response, which promotes relaxation and conserves energy.

The PNS is composed of sensory neurons, motor neurons, and interneurons. Sensory neurons are responsible for relaying sensory information from the body to the brain. Motor neurons are responsible for controlling movement and transmitting motor commands from the brain to the muscles. Interneurons are responsible for processing and integrating information between sensory and motor neurons.

Dysfunction of the PNS can lead to a variety of neurological disorders, such as peripheral neuropathy and Guillain-Barre syndrome. Treatments for PNS disorders may include medications, physical therapy, and other supportive therapies.

Somatic Nervous System

The somatic nervous system (SNS) is a part of the peripheral nervous system that is responsible for controlling voluntary movements and relaying sensory information from the body to the brain.

The SNS is composed of sensory neurons that transmit information about touch, pain, temperature, and other sensations from the skin, muscles, and joints to the brain. Motor neurons in the SNS are responsible for controlling voluntary movements of the skeletal muscles, which are responsible for body movements such as walking and lifting.

The SNS is activated by signals from the brain, which are transmitted through the spinal cord to the motor neurons. These signals cause the motor neurons to release the neurotransmitter acetylcholine, which activates the muscles and causes them to contract.

The SNS also plays a role in reflexes, which are involuntary movements that occur in response to a stimulus. Reflexes are mediated by sensory neurons that send signals directly to motor neurons in the spinal cord, bypassing the brain.

Disorders of the SNS can lead to a variety of conditions, such as muscle weakness, spasms, and paralysis. Treatments for SNS disorders may include medications, physical therapy, and other supportive therapies.

Autonomic Nervous System (ANS)

The autonomic nervous system (ANS) is a part of the peripheral nervous system that is responsible for controlling involuntary functions of the body, such as heart rate, digestion, and breathing.

The ANS is divided into two main parts: the sympathetic nervous system and the parasympathetic nervous system. The sympathetic nervous system is responsible for the "fight or flight" response, which prepares the body for intense physical activity or stressful situations. The parasympathetic nervous system, on the other hand, is responsible for the "rest and digest" response, which promotes relaxation and conserves energy.

The sympathetic nervous system is activated in response to stress, danger, or other intense stimuli. This causes the release of the hormone adrenaline, which increases heart rate and blood pressure, dilates the pupils, and diverts blood flow away from the digestive system and toward the muscles, preparing the body for action.

The parasympathetic nervous system, on the other hand, is activated during periods of rest and relaxation. This causes the release of the hormone acetylcholine, which slows heart rate and breathing, constricts the pupils, and stimulates digestion.

The ANS also plays a role in the regulation of other bodily functions such as body temperature, urination, and sexual arousal.

Sympathetic and Parasympathetic Divisions of ANS

The autonomic nervous system (ANS) is divided into two main parts: the sympathetic nervous system and the parasympathetic nervous system. These two systems work together to regulate involuntary bodily functions such as heart rate, digestion, and breathing.

The sympathetic nervous system is responsible for the "fight or flight" response, which prepares the body for intense physical activity or stressful situations. When activated, the sympathetic nervous system causes the release of the hormone adrenaline, which increases heart rate and blood pressure, dilates the pupils, and diverts blood flow away from the digestive system and towards the muscles, preparing the body for action.

The parasympathetic nervous system, on the other hand, is responsible for the "rest and digest" response, which promotes relaxation and conserves energy. When activated, the parasympathetic nervous system causes the release of the hormone acetylcholine, which slows heart rate and breathing, constricts the pupils, and stimulates digestion.


The sympathetic and parasympathetic nervous systems often work in opposition to each other to maintain balance in the body. For example, the sympathetic nervous system may increase heart rate and blood pressure to respond to a stressful situation, while the parasympathetic nervous system will slow down heart rate and promote digestion when the body is at rest.

Dysfunction of the sympathetic and parasympathetic nervous systems can lead to a variety of conditions, such as hypertension, digestive disorders, and autonomic neuropathy. Treatments for these conditions may include medications, lifestyle changes, and other supportive therapies.

Sensory Systems

The sensory systems are responsible for receiving and processing information from the environment and transmitting it to the brain for interpretation. There are five main sensory systems: vision, hearing, taste, smell, and touch.

The visual system is responsible for processing light and color. The eye receives light and transmits visual information to the brain via the optic nerve. The brain then processes this information to create a visual representation of the environment.

The auditory system is responsible for processing sound. The ear receives sound waves and transmits auditory information to the brain via the auditory nerve. The brain then processes this information to create a perception of sound.

The gustatory system is responsible for processing taste. Taste receptors in the tongue detect different flavors and transmit this information to the brain via the gustatory nerve.

The olfactory system is responsible for processing smell. The nose contains olfactory receptors that detect different odors and transmit this information to the brain via the olfactory nerve.

The somatosensory system is responsible for processing touch and other bodily sensations. Nerve receptors throughout the body detect touch, temperature, pressure, and pain, and transmit this information to the brain via the somatosensory nerve.

The sensory systems work together to provide a comprehensive understanding of the environment. Dysfunction of the sensory systems can lead to a variety of conditions, such as blindness, deafness, anosmia (loss of smell), and sensory processing disorder. Treatments for sensory disorders may include medications, surgery, and supportive therapies such as assistive devices or sensory integration therapy.


Motor Systems

The motor systems are responsible for controlling movement and maintaining posture. There are two main types of motor systems: the somatic motor system and the autonomic motor system.

The somatic motor system controls voluntary movement and is responsible for moving the skeletal muscles. The brain sends motor commands through the spinal cord and to the muscles via the somatic motor nerves. This system is responsible for the movement of the limbs, trunk, and head.

The autonomic motor system controls involuntary movement and is responsible for regulating the activity of smooth muscles, cardiac muscles, and glands. This system is further divided into the sympathetic and parasympathetic nervous systems, which work together to regulate bodily functions such as heart rate, breathing, and digestion.

Dysfunction of the motor systems can lead to a variety of conditions, such as paralysis, tremors, and spasticity. Treatments for motor disorders may include medications, physical therapy, and surgery.

Higher Cognitive Functions

Higher cognitive functions refer to the complex mental processes that allow humans to think, reason, learn, and problem-solve. These functions are controlled by the cerebral cortex, which is the outer layer of the brain responsible for consciousness, perception, thought, and memory.

Some of the higher cognitive functions include:

Attention: 

the ability to focus on a task or stimulus while ignoring distractions.

Memory:

 the ability to store and retrieve information.

Language:

 the ability to communicate through speech and writing.

Perception: 

the ability to interpret sensory information and make sense of the world around us.

Executive functions:

 the ability to plan, organize, and regulate behavior.

Decision-making: 

the ability to analyze information and make choices.

Problem-solving:

 the ability to identify and solve problems.


Dysfunction of higher cognitive functions can lead to a variety of conditions, such as attention deficit hyperactivity disorder (ADHD), dementia, and traumatic brain injury. Treatments for cognitive disorders may include medications, cognitive-behavioral therapy, and supportive therapies such as occupational therapy or speech therapy.

Higher cognitive functions are essential for human intelligence and behavior, allowing us to interact with our environment and each other in complex and meaningful ways.

Disorders of the Nervous System

Disorders of the nervous system refer to a range of conditions that affect the structure or function of the brain, spinal cord, and nerves. These disorders can be caused by a variety of factors, including genetics, injury, infection, and degenerative diseases. Some common disorders of the nervous system include:

Epilepsy:

A neurological disorder characterized by recurrent seizures caused by abnormal electrical activity in the brain.

Parkinson's disease: 

A progressive disorder that affects movement, caused by the death of dopamine-producing cells in the brain.

Multiple sclerosis:

An autoimmune disorder that affects the myelin sheath that surrounds nerve fibers, leading to communication problems between the brain and the rest of the body.

Alzheimer's disease: 

A degenerative disorder that affects memory and cognitive function, causing a progressive decline in thinking, behavior, and social skills.

Migraine:

A neurological disorder characterized by recurrent headaches that may be accompanied by visual disturbances, nausea, and sensitivity to light and sound.

Stroke: 

A medical emergency is caused by an interruption of blood flow to the brain, leading to damage to brain tissue and loss of function.

Traumatic brain injury: 

A condition caused by a blow or jolt to the head that disrupts normal brain function, leading to a range of symptoms depending on the severity of the injury.

Treatment for disorders of the nervous system may vary depending on the underlying cause and symptoms and may include medications, surgery, physical therapy, and supportive therapies such as speech therapy or occupational therapy.

Current Research and Future Directions in Neuroscience

Neuroscience is a rapidly evolving field that continues to expand our understanding of the brain and nervous system. Some current areas of research and future directions in neuroscience include:

Neuroplasticity:

 the brain's ability to adapt and change in response to experience. Researchers are exploring how to harness this ability to treat neurological disorders such as stroke, traumatic brain injury, and neurodegenerative diseases.

Brain-machine interfaces:

 technology that allows direct communication between the brain and external devices, such as prosthetic limbs or computers. This field has the potential to revolutionize the way we interact with technology and restore function to individuals with disabilities.

Epigenetics:

 the study of how gene expression is influenced by environmental factors. Researchers are exploring how epigenetic changes may contribute to the development of neurological disorders and how they can be targeted for treatment.

Neurodegeneration:

 the progressive loss of function and structure in neurons, which underlies many neurological disorders. Researchers are working to understand the underlying mechanisms of neurodegeneration and develop new treatments to slow or prevent it.

Neural networks:

 the complex connections between neurons that allow the brain to process information and control behavior. Researchers are exploring how these networks function and how they can be manipulated to treat neurological disorders.

Neuromodulation:

 the use of electrical or chemical signals to modulate neural activity. Researchers are exploring how neuromodulation can be used to treat conditions such as depression, chronic pain, and epilepsy.

Conclusion

The nervous system is a complex and vital system that allows us to interact with our environment and control our body's functions. It is responsible for a wide range of processes, from sensory perception to higher cognitive functions. 

The nervous system is composed of the central nervous system, which includes the brain and spinal cord, and the peripheral nervous system, which includes the nerves that connect the central nervous system to the rest of the body. Neurons and glial cells are the basic building blocks of the nervous system, and they work together to transmit and process information.

 The autonomic nervous system plays a critical role in regulating the body's internal functions, while the somatic nervous system controls voluntary movements. There are many disorders that can affect the nervous system, from epilepsy to traumatic brain injury, and research is ongoing to develop new treatments and therapies for these conditions. 

The field of neuroscience is constantly expanding our understanding of the nervous system and has the potential to improve the lives of millions of people affected by neurological disorders.

FAQS

What are the 3 main parts of the nervous system?

The nervous system is divided into three main parts: the central nervous system (CNS), the peripheral nervous system (PNS), and the autonomic nervous system (ANS).

The CNS consists of the brain and spinal cord and is responsible for integrating and processing sensory information and controlling motor functions. The PNS includes all the nerves that extend from the CNS to the rest of the body, and it is responsible for transmitting sensory information to the CNS and carrying motor commands from the CNS to the muscles and organs. The ANS is a specialized part of the PNS that regulates the body's internal environment and controls involuntary functions, such as heart rate, breathing, and digestion.


What are the 7 parts of the nervous system?

There are several ways to categorize the parts of the nervous system, but one common method is to divide it into seven main parts:

Brain: The brain is the most complex organ in the body and is responsible for processing and integrating sensory information, controlling motor functions, and regulating many of the body's internal processes.

Spinal cord: The spinal cord is a long, thin bundle of nerves that extends from the brain down the back. It serves as a conduit for signals between the brain and the rest of the body, and also plays a role in reflexes.

Nerves: Nerves are bundles of fibers that transmit information between the brain, spinal cord, and the rest of the body. They can be divided into two main types: sensory nerves, which carry information from the body to the brain, and motor nerves, which carry commands from the brain to the muscles and organs.

Neurons: Neurons are specialized cells that transmit electrical and chemical signals in the nervous system. They are the basic building blocks of the nervous system and are responsible for processing and transmitting information.

Glial cells: Glial cells are non-neuronal cells that provide support and protection for neurons. They play a critical role in maintaining the health and function of the nervous system.

Autonomic nervous system (ANS): The ANS is a specialized part of the nervous system that regulates the body's internal environment and controls involuntary functions such as heart rate, breathing, and digestion.

Somatic nervous system (SNS): The SNS is responsible for controlling voluntary movements and transmitting sensory information from the body to the brain. It is involved in a wide range of functions, from muscle control to touch and pain perception.

What are the 4 major organs of the nervous system?

The nervous system is a complex system that includes several organs and structures. However, the four major organs of the nervous system are:

Brain: The brain is the most complex organ in the nervous system, and it is responsible for controlling and coordinating all the body's functions. It receives sensory information from the environment and processes it to generate appropriate motor responses.

Spinal cord: The spinal cord is a long, thin bundle of nerves that extends from the brain down the back. It serves as a conduit for signals between the brain and the rest of the body and also plays a role in reflexes.

Nerves: Nerves are bundles of fibers that transmit information between the brain, spinal cord, and the rest of the body. They can be divided into two main types: sensory nerves, which carry information from the body to the brain, and motor nerves, which carry commands from the brain to the muscles and organs.

Sensory organs: Sensory organs are specialized organs that detect stimuli from the environment and transmit sensory information to the brain. The major sensory organs include the eyes, ears, nose, tongue, and skin.

What are the 3 types of neurons?

The three types of neurons in the nervous system are:

Sensory neurons: These neurons are responsible for detecting stimuli from the environment and transmitting sensory information to the brain and spinal cord. They have specialized receptors in the skin, muscles, and other tissues that detect stimuli such as touch, pain, temperature, and pressure.

Motor neurons: These neurons are responsible for controlling voluntary and involuntary movements by transmitting signals from the brain and spinal cord to the muscles and glands of the body. They can be further divided into two subtypes: somatic motor neurons that control skeletal muscles and autonomic motor neurons that control smooth muscles, cardiac muscles, and glands.

Interneurons: These neurons are responsible for processing and integrating information within the brain and spinal cord. They receive input from sensory neurons and transmit output to motor neurons, and they are responsible for generating complex behaviors, thoughts, and emotions. Interneurons are the most numerous and diverse type of neurons in the nervous system.


What are nerves made of?

Nerves are made up of bundles of nerve fibers, which are long, slender projections of neurons. Nerve fibers consist of a central core of axons, which are covered by layers of specialized cells called glia. The axons are the part of the neuron that transmit electrical signals, or action potentials, over long distances. They are surrounded by the myelin sheath, a fatty substance that helps to insulate the axon and speed up the transmission of signals. The glial cells that surround the axons are also important for maintaining the structure and function of the nervous system. Together, the nerve fibers and glial cells form the basic building blocks of nerves, which are responsible for transmitting information throughout the body.


Is nervous an organ?

The nervous system is not a single organ, but rather a complex network of organs, tissues, and cells that work together to control and coordinate the functions of the body. The nervous system includes the brain, spinal cord, nerves, and sensory organs such as the eyes and ears. The brain and spinal cord are often referred to as the central nervous system, while the nerves and sensory organs make up the peripheral nervous system. So, while the nervous system is not a single organ, it is a collection of organs and structures that work together to regulate and coordinate the body's functions.


What is the 12 nervous system?

There is no such thing as the 12 nervous system. The human nervous system is typically divided into two main parts: the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS consists of the brain and spinal cord, while the PNS consists of all the other nerves in the body that are not part of the CNS. The PNS is further divided into the somatic nervous system, which controls voluntary movements, and the autonomic nervous system, which controls involuntary functions such as heart rate and digestion. Within the autonomic nervous system, there are two subdivisions: the sympathetic nervous system and the parasympathetic nervous system.


What is the largest nerve in the body?

The largest nerve in the body is the sciatic nerve. The sciatic nerve is a thick and long nerve that runs from the lower back down to the legs and feet. It is formed by several smaller nerves that come together in the lower back and is approximately as thick as the human thumb. The sciatic nerve is responsible for transmitting sensory and motor signals between the spinal cord and the leg muscles and skin. It is the main nerve that provides movement and sensation to the lower extremities of the body.


What is the scientific name for a nerve cell?

The scientific name for a nerve cell is a neuron. Neurons are specialized cells that transmit electrical and chemical signals throughout the nervous system. They are the basic building blocks of the nervous system and play a critical role in regulating and coordinating the functions of the body. Neurons are composed of three main parts: the cell body, dendrites, and axon. The cell body contains the nucleus and other organelles that are necessary for the neuron's normal functioning. Dendrites are the branch-like projections of the neuron that receive signals from other neurons. The axon is a long, slender projection that transmits signals to other neurons or to other cells in the body, such as muscle cells or gland cells.


What are the 5 major functions of the nervous system?

The nervous system performs many vital functions in the body. Some of the major functions of the nervous system include:

Sensory input: The nervous system receives information from sensory organs such as the eyes, ears, nose, and skin, and sends this information to the brain for processing.

Integration: The nervous system integrates sensory information from multiple sources to make decisions and coordinate responses to various stimuli.

Motor output: The nervous system sends signals to muscles and glands to produce movement or activate secretions, such as saliva or sweat.

Homeostasis: The nervous system helps to maintain a stable internal environment in the body by regulating various functions, including heart rate, blood pressure, and body temperature.

Higher cognitive functions: The nervous system is involved in higher cognitive functions such as memory, learning, language, and emotion. It allows us to think, reason, and communicate with others.











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